2-,3-,4-,5-,6-,7-,8-,9-and/or 10-substituted dibenzoxazepine...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 413/06 (2006.01) A61K 31/55 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2159990

The present invention provides substituted dibenzoxazepine compounds of formula (1), which as useful as analgesic agents for the treatment of pain, and as prostaglandin-E2 antagonists for the treatment of prostaglandin-E2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of formula (I) in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin-E2 mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of formula (I) to the animal.

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