2,3,4,5-tetrahydro-1h-¬1,4|-benzodiazepine-3-hydroxamic...

Details 2,3,4,5-tetrahydro-1h-¬1,4|-benzodiazepine-3-hydroxamic... 2,3,4,5-tetrahydro-1h-¬1,4|-benzodiazepine-3-hydroxamic...

C - Chemistry, Metallurgy

07

D

C07D 243/14 (2006.01) A61K 31/395 (2006.01) C07D 401/06 (2006.01) C07D 403/10 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2317546

Compounds are provided having formula (I), wherein R, R1, R2, R3 and R4 are defined in the specification, which have matrix metalloproteinase inhibiting activity.

L'invention se rapporte à des composés représentés par la formule (I) dans laquelle R, R¿1?, R¿2?, R¿3? et R¿4? sont définis dans la description. Ces composés présentent une activité inhibitrice vis à vis des métalloprotéases matricielles.

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