2' -¬(3,6-dihydro-phenyl-1(2h)pyridinyl or phenyl-1-...

C - Chemistry – Metallurgy – 07 – D

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260/294, 260/292

C07D 211/34 (2006.01) C07D 211/14 (2006.01) C07D 211/70 (2006.01) C07D 313/10 (2006.01)

Patent

CA 1089467

Abstract Compounds which are useful as anti-inflammatory agents have the formula Image wherein X is a member selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halogen, amino, tri- fluoromethyl and nitro; Y and Y' are the same and are members selected from the group consisting of hydrogen, halogen, tri- fluoromethyl, lower alkyl, lower alkoxy, nitro, amino and cyano, and Y is at the 4- or 5-position and Y' is at the 4'- or 3'-position, provided when Y is at the 4-position, Y' is at the 4'-position and when Y is at the 5-position, Y' is the 5'-position; Z is a straight or branched chain alkylene group containing from 2 to about 6 carbons; and pharmaceuti- cally acceptable acid- or base-addition salts thereof.

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