2,3,7-substituted imidazo-[1,2b]-pyridazines for treatment...

Details 2,3,7-substituted imidazo-[1,2b]-pyridazines for treatment... 2,3,7-substituted imidazo-[1,2b]-pyridazines for treatment...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/5025 (2006.01)

Patent

CA 2694261

Compounds of formula (I) in free or salt or solvate form, where R1, R2 and R5 have the meanings as indicated in the specification, are useful for treating diseases mediated by the ALK-5 and/or ALK-4 receptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

L'invention porte sur des composés de formule (I) sous forme libre, de sel ou de solvate, où R1, R2 et R5 ont les significations telles qu'indiquées dans la description, lesquels composés sont utiles pour le traitement de maladies à médiation par le récepteur ALK-5 et/ou ALK-4. L'invention porte également sur des compositions pharmaceutiques qui contiennent les composés et sur des procédés pour préparer les composés.

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