2,3-dihydro-2-benzofurancarboxamide derivatives

C - Chemistry – Metallurgy – 07 – D

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260/363.5, 260/3

C07D 409/04 (2006.01) C07D 307/85 (2006.01) C07D 409/10 (2006.01)

Patent

CA 1145758

ABSTRACT This invetation relates to 2,3-dihydro-2-benzofurancarboxamide derivatives. There are provided 2,3-dihydro-2-benzofurancarboxamide derivatives of formula Image (I) wherein R is a substituent at the 5-position on the 2,3-dihydrobenzofuran ring system and is a thienyl group, or a phenyl, phenoxy, benzyl or benzoyl group substituted by an alkoxy group of 1 to 6 carbon atoms, a 1-hydroxyethyl group or an acetamido group, or is a substituent at the 4-position on the 2,3-dihydro- benzofuran ring system and is a phenoxy group optionally substituted by alkyl or alkoxy of 1 to 6 carbon atoms, acetamido, 1-hydroxyethyl or nitro. 2,3- dihydro-2-benzofurancarboxamide derivatives of formula I have exhibited lipogenesis inhibiting activity and thus find use in animal husbandry to pro- vide a leaner carcass after slaughter.

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