2-(3-oxoalk(en)yl)-3-isothiazolones and derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 275/00 (2006.01) A01N 43/80 (2006.01) C07D 275/03 (2006.01) C07D 417/06 (2006.01) A61K 7/00 (1990.01)

Patent

CA 2113700

ABSTRACT Antimicrobial compounds of the formula Image Image I or II wherein R is hydrogen, halogen, or (C1-4)alkyl group; R1 is hydrogen or halogen; alternatively, R and R1 may be taken together with the carbons to which they are attached to form a 5- to 7-membered carbocyclic ring, said ring optionally being aromatic; R2 is hydrogen or (C1-3)alkyl group; and R3 is hydrogen, substituted or unsubstituted (C1-C18)alkyl, substituted or unsubstituted (C2-C18)alkenyl, substituted or unsubstituted (C2-C18)alkynyl, substituted or unsubstituted (C4-C8)cycloalkyl or cycloalkenyl, substituted or unsubstituted (C6-C10)aryl or arylalkyl group are disclosed.

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