2,3-substituted 5,6-diaryl-pyrazine derivatives as cb1...

Details 2,3-substituted 5,6-diaryl-pyrazine derivatives as cb1... 2,3-substituted 5,6-diaryl-pyrazine derivatives as cb1...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01)

Patent

CA 2527037

The present invention relates to 2,3-substituted 5,6-diaryl-pyrazine derivatives, e.g. 5,6-diaryl-3-heterocyclylpyrazine-2-ester derivatives of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutical compositions containing them. The compounds are cannabinoid receptor 1 (CB1) modulators.

La présente invention concerne des dérivés de 5,6-diaryl-pyrazine 2,3-substituée, tels que des dérivés de 5,6-diaryl-3-hétérocyclylpyrazine-2-ester représentés par la formule générale (I), des procédés destinés à la préparation de ces composés, l'utilisation de ces composés dans le traitement de l'obésité, de troubles psychiatriques et de troubles neurologiques, des procédés thérapeutiques utilisant ces composés et des compositions pharmaceutiques contenant ces composés. Ces composés sont des modulateurs du récepteur cannabinoïde 1 (CB1).

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