2, 4, 5-substituted piperidines as renin inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 413/12 (2006.01) A61K 31/445 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2601702

Novel substituted piperidines of the general formula (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are highly potent.

L'invention concerne de nouvelles pipéridines substituées représentées par les formules générales (I) et (II) définies telles que dans la description. Les composés sont particulièrement adaptés en tant qu'inhibiteurs de la rénine, et sont hautement puissants.

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