2, 4, 6-trisubstituted pyrimidines as phosphotidylinositol...

Details 2, 4, 6-trisubstituted pyrimidines as phosphotidylinositol... 2, 4, 6-trisubstituted pyrimidines as phosphotidylinositol...

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2571750

The invention concerns pyrimidine derivatives of Formula (I) wherein each of Qa, G1, G2, q, R3, r, R4, X1 and Qb have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the production of an anti-proliferative effect in a warm-blooded animal such as man.

L'invention concerne des dérivés de pyrimidine représentés par la formule (I), dans laquelle Qa, G1, G2, q, R3, r, R4, X1 et Qb ont chacun les significations définies dans le descriptif, des procédés permettant de préparer ces dérivés, des compositions pharmaceutiques contenant ces dérivés, et l'utilisation de ces dérivés pour la préparation d'un médicament destiné à produire un effet anti-prolifératif chez un animal à sang chaud, en particulier chez l'homme.

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