2, 4, 6-trisubstituted pyrimidines as phosphotidylinositol...

Details 2, 4, 6-trisubstituted pyrimidines as phosphotidylinositol... 2, 4, 6-trisubstituted pyrimidines as phosphotidylinositol...

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2571748

The invention concerns pyrimidine derivatives of Formula (I) wherein each of p, R1, R2, q, R3, r, R4, X1 and Q1 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the production of an anti-proliferative effect in a warm-blooded animal such as man.

Cette invention concerne des dérivés de pyrimidine représentés par la formule (I) , dans laquelle, chacun des p, R1, R2, q, R3, r, R4, X1 et Q1 est tels que défini dans la description. Cette invention concerne également des procédés permettant de préparer de tels dérivés; des compositions pharmaceutiques contenant ces dérivés et leurs utilisations dans la fabrication d'un médicament utilisé pour produire un effet anti-proliférant chez un animal à sang chaud, tel qu'un être humain.

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