2,4 di (hetero) -arylamino-pyrimidine derivatives as zap-70...

Details 2,4 di (hetero) -arylamino-pyrimidine derivatives as zap-70... 2,4 di (hetero) -arylamino-pyrimidine derivatives as zap-70...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/506 (2006.01) C07D 239/48 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2538909

Disclosed are pyrimidine derivatives of formula (I); wherein R0, R1, R3 to R9, and Z have a signification as indicated in claim 1, which have ZAP-70 and/or Syk inhibitory activities.

L'invention concerne des dérivés de pyrimidine de formule (I), dans laquelle R?0¿, R?1¿, R?3¿ à R?9¿ et Z ont la signification indiquée dans la revendication 1, lesquels dérivés possèdent des activités inhibitrices des kinases ZAP-70 et/ou Syk.

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