2,4-di (phenylamino) pyrimidines useful in the treatment of...

Details 2,4-di (phenylamino) pyrimidines useful in the treatment of... 2,4-di (phenylamino) pyrimidines useful in the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/506 (2006.01) A61K 35/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2538413

There is provided a method of preventing or treating proliferative disorders such as a tumor disease, by inhibiting ALK activity with compounds of formula (I) wherein X, R1, R2 , R3 , R4 , R5, R6, R7,R8 and R9 are as indicated in claim 1.

L'invention concerne une méthode de prévention ou de traitement de troubles prolifératifs, tels qu'une maladie tumorale, consistant à inhiber l'activité de l'ALK, au moyen de composés de formule (I), dans laquelle X, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿ et R?9¿ sont tels que définis dans la revendication 1.

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