2-4-diaminopyrimidine derivatives

Details 2-4-diaminopyrimidine derivatives 2-4-diaminopyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/505 (2006.01) A61P 35/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2479133

There are provided compounds of formula (I), wherein X, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as indicated in claim 1, useful in disorders where ZAP- 70 and/or Syk inhibition plays a role or caused by a malfunction of signal cascades connected with FAK.

L'invention concerne des composés représentés par la formule (I), où X, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿ et R?9¿ sont tels que définis dans la revendication n·1. Lesdits composés sont utiles pour le traitement de troubles induits par l'inhibition de ZAP-70 et/ou Syk, ou causés par un dysfonctionnement de cascades de signaux liées à FAK.

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