2,4-dioxo-pyrido[2,3-d]pyrimidine-3-acetic acids and esters...

Details 2,4-dioxo-pyrido[2,3-d]pyrimidine-3-acetic acids and esters... 2,4-dioxo-pyrido[2,3-d]pyrimidine-3-acetic acids and esters...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/505 (2006.01) C07D 213/80 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2100164

2100164 9212979 PCTABS00014 A series of novel 2,4-dioxo-pyrido 2,3-d pyrimidine-3-acetic acids and their esters and pharmaceutically acceptable base addition salts are disclosed. These compounds are useful in therapy as aldose reductase inhibitors for the control of certain chronic diabetic complications. Methods for preparing these compounds from known starting materials are provided.

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