2-¬4-(diphenylmethylene)-1-piperidinyl|-acetic acids and...

Details 2-¬4-(diphenylmethylene)-1-piperidinyl|-acetic acids and... 2-¬4-(diphenylmethylene)-1-piperidinyl|-acetic acids and...

C - Chemistry, Metallurgy

07

D

260/292.2

C07D 211/08 (2006.01) C07D 211/70 (2006.01)

Patent

CA 1167446

A B S T R A C T New 2-[4-(diphenylmethylene)-1-piperidinyl]-acetic acids and their amides, processes for the preparation thereof and therapeutic compositions. These compounds have the formula Image wherein Y = -OH or -NR1R2, R1 and R2 = H, alkyl or phenyl; X = H, halogen or alkoxy; m = 0, 1 or 2 and n = 1 or 2. The 2-[4-(diphenylmethylene)-1-piperidinyl]-acetic acids are prepared by hydrolyzing the corresponding amide or lower alkyl ester, whereas the amides are prepared either by reacting a 4-(diphenylmethylene)-piperidine with an omega-haloacetamide, or by reacting an alkali metal salt of an omega-[4-diphenylmethylene)-1-piperidinyl]-alkanol (m = 1 or 2) with a 2-haloacetamide, or by reacting a nitrogen compound (HNR1R2) with a halide or alkyl ester of a 2-[4-(diphenylmethylene)-1-piperidinyl]-acetic acid. These compounds have in particular an antiallergic, spasmolytic, anti- histaminic and broncholytic activity.

386145

Affiliated with

Also associated with

Rating

2-¬4-(diphenylmethylene)-1-piperidinyl|-acetic acids and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-¬4-(diphenylmethylene)-1-piperidinyl|-acetic acids and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-¬4-(diphenylmethylene)-1-piperidinyl|-acetic acids and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1188291