2- (4-oxo-1-phenyl-1,3,8-triazaspiro 4.5 decan-8- yl)alkyl...

Details 2- (4-oxo-1-phenyl-1,3,8-triazaspiro 4.5 decan-8- yl)alkyl... 2- (4-oxo-1-phenyl-1,3,8-triazaspiro 4.5 decan-8- yl)alkyl...

C - Chemistry, Metallurgy

07

D

260/277.3

C07D 471/10 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 401/06 (2006.01) C07D 471/00 (2006.01) C07D 487/10 (2006.01)

Patent

CA 1085851

Abstract New compounds, which exhibit antidepressant activity and are also useful as antiinflammatory agents, have the following formula Image wherein R1 and R2 are independently selected from hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, tri- fluoromethyl, amino, nitro and cyano; R3 is selected from hydrogen, lower alkyl and lower alkenyl; R4 is selected from hydrogen, lower alkyl and halogen, and A is a straight or branched chain alkylene of 1 to 8 carbons; and a pharma- ceutically acceptable acid addition salt thereof.

254042

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