C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/279.35, 260/
C07D 407/10 (2006.01) C07D 211/52 (2006.01)
Patent
CA 1081233
ABSTRACT OF THE DISCLOSURE Tetralone and indanone compounds of the formula Image wherein R1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of 3-6 carbon atoms, F, Cl, Br, alkanoyloxy of 1-6 carbon atoms; R2 is OH or alkoxy of 1-4 carbon atoms or R1 and R2 collectively are methylenedioxy; R3 is H or CH3; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, F, Cl, Br or CF3; n is 1 or 2, and physiological- ly acceptable acid addition salts thereof, are central nervous system depressants. They may be prepared by certain specified and recited reactions of compounds containing the grouping Image or pracursions thereof.
246346
Irmscher Klaus
Jonas Rochus
Muller-Calgan Helmut
Uhl Jurgen
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