2-(4-pyridylaminometyl)-benzimidazole derivatives having...

Details 2-(4-pyridylaminometyl)-benzimidazole derivatives having... 2-(4-pyridylaminometyl)-benzimidazole derivatives having...

C - Chemistry, Metallurgy

07

D

167/231, 260/280

C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1279648

ABSTRACT OF THE DISCLOSURE Provided herein is 2-(4-pyridylaminomethyl)benzimida- zole derivatives of the following general formula: Image and 75 novel benzimidazole derivatives are exemplified with a melting point and some of their preparing processes are described. The potent in vitro and in vivo antipicornavirus activities of the compounds of this invention are demon- strated. Some of the compounds of this invention is expected for preventing and treating picornavirus disease.

541384

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