C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/04 (2006.01) A61K 31/16 (2006.01) C07C 237/06 (2006.01) C07C 323/32 (2006.01) C07C 323/36 (2006.01)
Patent
CA 2226894
Novel 2-(4-substituted)-benzylamino-2-methyl-propanamides compounds, having CNS activity, of general formula (I) wherein: n is zero, 1, 2 or 3; X is -O-, -S-, -CH2- or -NH-; each of R and R1 independently is hydrogen, C1-C6 alkyl, halogen, hydroxy, C1-C4 alkoxy or trifluoromethyl; each of R2, R3 and R4 independently is hydrogen, C1-C6 alkyl or C3-C7 cycloalkyl; and the pharmaceutically acceptable salts thereof, are disclosed.
L'invention concerne les dérivés de 2-(4-substitué)-benzylamino-2-méthylpropanamides qui agissent sur le système nerveux central, représentés par la formule générale (I), où n vaut zéro, 1, 2 ou 3; X est -O-, -S-, -CH2- ou -NH-; R et R1 représentent chacun indépendamment hydrogène, alkyle C1-C6, halogène, hydroxy, alcoxy C1-C4 ou trifluorométhyle; R2, R3 et R4 représentent chacun indépendamment hydrogène, alkyle C1-C6 ou cycloalkyle C3-C7. L'invention concerne également les sels pharmaceutiquement acceptables de ces dérivés.
Amici Raffaella
Bonsignori Alberto
Pevarello Paolo
Salvati Patricia
Varasi Mario
Fetherstonhaugh & Co.
Newron Pharmaceuticals S.p.a.
Pharmacia & Upjohn S.p.a.
LandOfFree
2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2071042