C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/404 (2006.01) A61K 31/4184 (2006.01) A61P 7/02 (2006.01) C07C 69/738 (2006.01) C07C 205/56 (2006.01) C07D 209/18 (2006.01) C07D 209/20 (2006.01) C07D 235/18 (2006.01) C07D 403/10 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2452391
The present invention relates to novel inhibitors of formula (I) of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders. Processes for preparing these inhibitors are also disclosed.
La présente invention concerne de nouveaux inhibiteurs des facteurs VIIa, IXa, Xa, XIa, en particulier du facteur VIIa, représentés par la formule (I), des compositions pharmaceutiques contenant ces inhibiteurs et des méthodes comprenant l'utilisation de ces inhibiteurs pour le traitement ou la prévention des troubles thrombo-emboliques. L'invention concerne également des procédés permettant de préparer ces inhibiteurs.
Hendrix John
Hu Huiyong
Kolesnikov Aleksandr
Rai Roopa
Shrader William Dvorak
Axys Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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