C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/08 (2006.01) A61K 31/496 (2006.01) A61P 1/00 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2517146
The invention provides compounds of the formula (I), and pharmaceutically acceptable salts or prodrugs thereof, wherein, n, X, Y, R1, R2, R3, R4 and R5 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula (I) as 5- HT6 modulators for the treatment of central nervous system disorders.
L'invention se rapporte à des composés de formule (I), ainsi qu'à des sels pharmaceutiquement acceptables ou des promédicaments de ces composés. Dans ladite formule (I), n, X, Y, R?1¿, R?2¿, R?3¿, R?4 ¿et R?5¿ sont tels que définis dans la description. Cette invention concerne en outre des procédés permettant de préparer les composés de formule (I), des compositions les contenant, ainsi que des procédés permettant de les utiliser en tant que modulateurs des 5-HT¿6? pour traiter des troubles du système nerveux central.
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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