(2,5-dioxoimidazolidin-1-yl)-n-hydroxy-acetamides as...

Details (2,5-dioxoimidazolidin-1-yl)-n-hydroxy-acetamides as... (2,5-dioxoimidazolidin-1-yl)-n-hydroxy-acetamides as...

C - Chemistry, Metallurgy

07

D

C07D 233/74 (2006.01) C07D 233/76 (2006.01) C07D 233/78 (2006.01)

Patent

CA 2628159

The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are among other things useful for the treatment of obstructive airway diseases, such as chronic obstructive pulmonary disease (COPD).

La présente invention concerne des composés de formule (I) où les variables sont telles que définies dans la description. Les composés selon l'invention sont des inhibiteurs de la métalloprotéinase MMP-12 et peuvent entre autres choses être employés dans le traitement de maladies obstructives des voies respiratoires, telles que la bronchopneumopathie chronique obstructive (BPCO).

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