C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/78 (2006.01) A61K 31/165 (2006.01) A61K 31/4166 (2006.01) A61P 11/06 (2006.01) A61P 17/02 (2006.01) A61P 17/06 (2006.01) A61P 19/00 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) A61P 41/00 (2006.01) C07C 233/01 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2495853
The invention provides compounds of formula (I) in which L, X, Y, Z1, Z2, R1, R2, R3 and G2 have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy. The compounds of the invention are inhibitors of metalloproteinase MMP12 and are among other things useful for the treatment of obstructive airways diseases, such as asthma and chronic obstructive pulmonary disease (COPD).
L'invention concerne des composés de formule (I), dans laquelle L, X, Y, Z?1¿, Z?2¿, R?1¿, R?2¿, R?3¿ et G?2¿ sont tels que définis dans le descriptif ; leurs procédés de préparation ; les compositions pharmaceutiques les contenant ; un procédé de préparation des compositions pharmaceutiques et leur utilisation thérapeutique. Les composés de cette invention sont des inhibiteurs de la métalloprotéinase MMP12 et sont, entre autres, utilisés dans le traitement d'obstruction des voies ariennes, notamment l'asthme et la maladie pulmonaire obstructive chronique (MPOC).
Henriksson Krister
Munck Af Rosenschoeld Magnus
Astrazeneca Ab
Fetherstonhaugh & Co.
LandOfFree
2,5-dioxoimidazolidin-4-yl acetamides and analogues as... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2,5-dioxoimidazolidin-4-yl acetamides and analogues as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2,5-dioxoimidazolidin-4-yl acetamides and analogues as... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2072739