2,5-disubstituted arylsulfonamide ccr3 antagonists

Details 2,5-disubstituted arylsulfonamide ccr3 antagonists 2,5-disubstituted arylsulfonamide ccr3 antagonists

C - Chemistry, Metallurgy

07

D

C07D 211/96 (2006.01) A61K 31/445 (2006.01) A61P 11/06 (2006.01) A61P 25/28 (2006.01) C07C 311/29 (2006.01) C07D 241/04 (2006.01) C07D 243/08 (2006.01) C07D 295/26 (2006.01) C07D 403/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2758985

Provided herein are 2,5-disubstituted arylsulfonamides that are useful for modulating CCR3 activity, and pharma-ceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a CCR3 -mediated disorder, disease, or condition.

Linvention concerne des arylsulfonamides 2,5-disubstitués utilisés pour la modulation de l'activité de CCR3, et des compositions pharmaceutiques de ceux-ci. L'invention concerne en outre des méthodes d'utilisation des arylsulfonamides pour la prévention, le traitement ou l'amélioration d'un ou de plusieurs symptômes de troubles, maladies ou affections médiés par CCR3.

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