2,5-disubstituted piperidines

Details 2,5-disubstituted piperidines 2,5-disubstituted piperidines

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/538 (2006.01) A61P 9/12 (2006.01) C07D 405/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2660667

The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R1 and X are each as defined in detail in the description, and pharmaceutical preparations comprising these compounds.

La présente invention concerne des pipéridines 2,5-disubstituées, leur préparation et leur utilisation en tant que médicaments, en particulier en tant qu'inhibiteurs de la rénine, répondant à la formule générale (I) où R, R1 et X sont tels que définis dans la description, ainsi que des préparations pharmaceutiques comprenant ces composés.

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