2, 6 bisheteroaryl-4-aminopyrimidines as adenosine receptor...

Details 2, 6 bisheteroaryl-4-aminopyrimidines as adenosine receptor... 2, 6 bisheteroaryl-4-aminopyrimidines as adenosine receptor...

C - Chemistry, Metallurgy

07

D

C07D 405/14 (2006.01) A61K 31/506 (2006.01) A61P 9/00 (2006.01) A61P 11/06 (2006.01) A61P 37/00 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2551944

4-Aminopyrimidine derivatives of formula (I) FORMULA heteroaryl groups, including pharmaceutically acceptable salts thereof, wherein R1 and R2 are adenosine A2A receptor antagonists useful in the treatment of movement disorders such as Parkinson's disease.

La présente invention se rapporte à des dérivés 4-aminopyrimidines représentés par la formule (I) ainsi qu'à des sels pharmaceutiquement acceptables de ces dérivés. Dans la formule (I), R?1¿ et R?2¿ sont des groupes hétéroaryle, lesdits dérivés étant des antagonistes des récepteurs de l'adénosine A¿2A? utiles pour le traitement des troubles moteurs, par exemple de la maladie de Parkinson.

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