2,6-disubstituted penem compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 499/00 (2006.01) A61K 31/12 (2006.01) A61K 31/43 (2006.01) C07D 205/08 (2006.01) C07D 205/09 (2006.01) C07D 209/48 (2006.01) C07D 499/88 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01) C07F 9/568 (2006.01) C07F 9/6539 (2006.01) C07F 9/6558 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1136617

Abstract This invention relates to 2-substituted and 2,6-disubstituted penem compounds of the formula Image wherein Y is hydrogen, halo or certain organic radicals and X represents certain hetero-interrupted substituted alkyl radicals. Also included in the invention are pharma- ceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3-position is protected as by an easily removable ester protecting group, The compounds of the present invention are potent antibacterial agents or are of use as intermediates in the preparation of such agents.

342049

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