C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 455/00 (2006.01) A61K 31/435 (2006.01) C07D 471/18 (2006.01)
Patent
CA 2130563
This invention relates to 5-chloro-2, 3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acid-octahydro-3-hydroxy-2,6-metha- no-2H-quinolizin-8-yl ester (I), a novel 5-HT3-receptor antagonist, its method of preparation, and to its end-use application in the treatment of radio- and chemo-therapeutically-induced nausea and vomiting, in the treatment of pain associated with migraine, in the treatment of cognitive disorders, in treating hallucinatory endogenous psychoses of the type manifested in patients suffering from schizophrenia and mania, for irritable bowel syndrome, and to combat drug abuse.
Ester d'octahydro-3-hydroxy-2,6-méthano-2H-quinolizine-8-ylique (I) de l'acide 5-chloro-2, 3-dihydro-2,2-diméthylbenzofurane-7-carboxylique, un nouvel antagoniste du récepteur 5-HT3, son mode de préparation et son application finale dans le traitement des nausées et vomissements chimio-induits, de la douleur associée à la migraine, des troubles cognitifs, des psychoses endogènes hallucinatoires du type dont souffrent les patients atteints de manie et de schizophrénie et dans le traitement du syndrome du côlon irritable et de la toxicomanie.
Merrell Dow Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
2,6-methano-2h-quinolizin derivative as 5-ht3-receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2,6-methano-2h-quinolizin derivative as 5-ht3-receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2,6-methano-2h-quinolizin derivative as 5-ht3-receptor... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1545081