2,8-disubstituted quinazolinones

Details 2,8-disubstituted quinazolinones 2,8-disubstituted quinazolinones

C - Chemistry, Metallurgy

07

D

C07D 239/91 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/695 (2006.01) C07D 405/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2167345

2,8-Disubstituted quinazolinones are prepared by first subjecting the quinazolinone basic skeleton to condensation by customary reactions and then introducing the desired substituents into the 8-position. The compounds are suitable as active compounds in medicaments, in particular for the treatment of inflammations, thromboembolic diseases and cardiovascular diseases.

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