2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process...

Details 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process... 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process...

C - Chemistry, Metallurgy

07

D

260/265.5

C07D 471/06 (2006.01) C07D 217/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 1036606

ABSTRACT OF THE DISCLOSURE 2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula Image wherein COR is the acyl radical of an organic carboxylic acid of up to 26 carbon atoms excepting benzoic acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo- 1, 2, 3, 6, 7, 11b-hexahydro-4H-pyrazino-[2,1-a] isoquinoline with an acid or a reactive functional derivative thereof, e.g., an amhydride, a halogenide, an alkyl ester, a lactone or an azide.

216069

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