2-acylaminothiazole derivative or salt thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/04 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/439 (2006.01) A61K 31/4545 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61K 31/498 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61K 31/538 (2006.01) A61K 31/55 (2006.01) A61K 31/695 (2006.01) A61P 7/00 (2006.01) A61P 43/00 (2006.01) C07D 277/44 (2006.01) C07D 277/46 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01)

Patent

CA 2472711

A 2-acylaminothiazole derivative or a pharmaceutically acceptable salt thereof having an excellent effect of proliferating human c-mpl-Ba/F3 cells and an activity of increasing platelets based on the effect of promoting the formation of megakaryocytic colonies. A compound or a pharmaceutically acceptable salt thereof useful in treating thrombopenia.

L'invention concerne un dérivé de 2-acylaminothiazole ou un sel pharmaceutiquement acceptable de celui-ci possédant un excellent effet de prolifération de cellules c-mpl-Ba/F3 humaines et une activité d'augmentation des plaquettes basée sur l'effet d'accélération de la formation de colonies de mégakaryocytes. L'invention concerne également un composé ou un sel pharmaceutiquement acceptable de celui-ci utilisé pour traiter la plaquettopénie.

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