2-alkylidene-19-nor-vitamin d derivatives for the treatment...

A - Human Necessities – 61 – K

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Details

A61K 31/59 (2006.01) A61P 3/02 (2006.01) A61P 21/00 (2006.01)

Patent

CA 2538993

The present invention relates to methods of treating frailty, muscle damage or sarcopenia, the methods comprising administering to a patient in need thereof a 2-alkylidene-19-nor-vitamin D derivative. Particularly, the present invention relates to methods of treating frailty, muscle damage or sarcopenia, the methods comprising administering to a patient in need thereof a therapeutically effective amount of 2-methylene-19-nor-20(S)-1.alpha.,25- dihydroxyvitamin D3.

L'invention concerne des méthodes pour traiter un état de santé fragile, les lésions musculaires ou la sarcopénie, ces méthodes consistant à administrer à un patient nécessitant un tel traitement un dérivé de la 2-alkylidène-19-nor-vitamine D. Plus particulièrement, la présente invention concerne des méthodes pour traiter un état de santé fragile, les lésions musculaires ou la sarcopénie, ces méthodes consistant à administrer à un patient nécessitant un tel traitement une quantité thérapeutiquement efficace de 2-méthylène-19-nor-20(S)-1.alpha.,25-dihydroxyvitamine D¿3?.

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