2-amidobenzothiazoles as cb1 receptor inverse agonists

Details 2-amidobenzothiazoles as cb1 receptor inverse agonists 2-amidobenzothiazoles as cb1 receptor inverse agonists

A - Human Necessities

61

K

A61K 31/428 (2006.01) A61P 3/04 (2006.01) C07D 277/82 (2006.01)

Patent

CA 2528785

The present invention relates to compounds of formula (I) wherein R1, R2, R3, R3a and R3b are as defined in the description and claims, and pharmaceutically acceptable salts thereof, for use as therapeutically active substances. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.

La présente invention concerne des composés de formule (I), dans laquelle R?1¿, R?2¿, R?3¿, R?3a¿ et R?3b¿ sont tels que définis dans le mémorandum descriptif et dans les revendications, et des sels pharmaceutiquement acceptables desdits composés, destinés à être utilisés comme substances pharmaceutiquement actives. Les composés de l'invention sont utiles pour le traitement et/ou la prophylaxie de maladies associées à la modulation du récepteur CB1.

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