2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on...

C - Chemistry – Metallurgy – 07 – C

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C07C 217/14 (2006.01) A61K 31/135 (2006.01) A61K 31/21 (2006.01) A61K 31/395 (2006.01) A61K 31/675 (2006.01) C07C 217/20 (2006.01) C07C 219/26 (2006.01) C07C 271/20 (2006.01) C07C 271/44 (2006.01) C07D 207/34 (2006.01) C07D 213/79 (2006.01) C07D 215/48 (2006.01) C07D 261/18 (2006.01) C07F 9/12 (2006.01)

Patent

CA 2102490

Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene of formula (I) wherein R1 and R2, different from each other, are a hydrogen atom or an OY' group; Y and Y' are a hydrogen atom or an acyl group or a phenyl; m is 1 and 2; n is an integer from 3 to 7; R3 is hydrogen alkyl; R4 and R5, are hydrogen or halogen alkyl or alkoxy; and their use in therapeutic field ace described. The compounds are particularly useful in the treatment of arterial hypertension, cardiac decompensation and renal failure, in the treatment of peripheral arteriopathies and in cerebrovascular insufficiency.

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