2-amino-1,3-propanediol compound and immunosuppressant

Details 2-amino-1,3-propanediol compound and immunosuppressant 2-amino-1,3-propanediol compound and immunosuppressant

C - Chemistry, Metallurgy

07

C

C07C 215/02 (2006.01) A61K 31/13 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) C07C 215/10 (2006.01) C07C 215/18 (2006.01) C07C 215/20 (2006.01) C07C 215/24 (2006.01) C07C 215/26 (2006.01) C07C 215/28 (2006.01) C07C 215/34 (2006.01) C07C 215/42 (2006.01) C07C 215/54 (2006.01) C07C 215/56 (2006.01) C07C 215/68 (2006.01) C07C 217/28 (2006.01) C07C 217/30 (2006.01) C07C 217/34 (2006.01) C07C 217/48 (2006.01) C07C 217/52 (2006.01) C07C 217/64 (2006.01) C07C 217/72 (2006.01) C07C 217/76 (2006.01) C07C 219/

Patent

CA 2126337

2-Amino-1,3-propanediol compounds of the formula (I) (see formula I) wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R2, R3, R4 and R5 are the same or different and each is a hydrogen, an alkyl, an aralkyl, an acyl or an alkoxycarbonyl, pharmaceutically acceptable salts thereof and immunosuppressants comprising these compounds as active ingredients. The 2-amino-1,3-propanediol compounds of the present invention show immunosuppressive action and are useful for suppressing rejection in organ or bone marrow tranplantation, prevention and treatment of autoimmune diseases or as reagents for use in medicinal and pharmaceutical fields.

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