2-amino-1,3-thiazepines and their use as inhibitors of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 281/02 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01) C07D 417/00 (2006.01) C07D 513/10 (2006.01) C07F 9/6536 (2006.01)

Patent

CA 2165386

The present invention relates to 2-amino-1,3- thiazepines of the general formula I Image (I) in which W is CR1R2, X is CR20R21, Y is CR21R23 and Z is C24R25 and R1, R2, R20, R21, R22 and R23 have the meanings specified in Claim 1, which are inhibitors of nitric oxide synthase, and their use for the treatment of diseases which are caused by an increased nitric oxide level.

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