2-amino-3-(halobenzoyl)-methylphenylacetic acids, esters and...

Details 2-amino-3-(halobenzoyl)-methylphenylacetic acids, esters and... 2-amino-3-(halobenzoyl)-methylphenylacetic acids, esters and...

C - Chemistry, Metallurgy

07

C

260/477.6, 260/5

C07C 229/42 (2006.01) A61K 31/12 (2006.01) A61K 31/13 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) A61K 31/235 (2006.01) A61K 31/24 (2006.01) C07C 49/76 (2006.01) C07C 57/30 (2006.01) C07C 57/32 (2006.01) C07C 57/46 (2006.01)

Patent

CA 1173852

ABSTRACT OF THE DISCLOSURE Novel 2-amino-3-(halobenzoyl)methylphenylacetic acids, esters and salts having the formula: Image wherein R is selected from the group consisting of hydrogen, lower alkyl or a pharmaceutically acceptable metal cation, Y is halogen, and n is an integer of 1 to 3 are provided. The compounds exhibit outstanding anti-inflammatory and analgesic activity in warm blooded animals with minimal gastro-intestinal toxicity.

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