2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 295/155 (2006.01) A61K 31/40 (2006.01) C07D 295/135 (2006.01) C07D 307/79 (2006.01) C07D 333/54 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2004575

ABSTRACT The invention concerns a series of novel 2-amino- monomethoxycyclohexyl amides having analgesic and neuroprotective activity. The compounds bind selectively to the kappa opioid receptor. Pharmaceutical compositions containing the compounds, methods of using them, and processes for preparing them are also disclosed.

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