2-amino-4-phenylquinazoline derivatives and the use thereof...

Details 2-amino-4-phenylquinazoline derivatives and the use thereof... 2-amino-4-phenylquinazoline derivatives and the use thereof...

C - Chemistry, Metallurgy

07

D

C07D 239/84 (2006.01) A61K 31/517 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2608766

New phenylquinazoline derivatives of the formula (I) in which R1, R2, R3, R4 and R5 are as defined in claim 1 are HSP90 inhibitors and can be used for manufacturing a medicinal product for the treatment of diseases where the inhibition, regulation and/or modulation of HSP90 plays a part.

L'invention concerne de nouveaux dérivés de phénylchinazoline de la formule (I) où R1, R2, R3, R4 et R5 ont la signification données dans le revendication 1. Ces dérivés sont des inhibiteurs de HSP90 et peuvent servir à la production d'un médicament destiné au traitement de maladies où l'inhibition, la régulation et/ou modulation de HSP90 joue un rôle.

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