2-amino-4-substituted-5-hydroxypyrimidine derivatives useful...

Details 2-amino-4-substituted-5-hydroxypyrimidine derivatives useful... 2-amino-4-substituted-5-hydroxypyrimidine derivatives useful...

C - Chemistry, Metallurgy

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D

167/222, 260/261

C07D 239/47 (2006.01) A61K 31/505 (2006.01) C07D 239/46 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 1265519

HYDROXY AND ALKOXY PYRIMIDINES Abstract 2-Amino-4-substituted-5-(hydroxy or alkoxy)- pyrimidines, which may be 6-substituted, and deriva- tives thereof are inhibitors of leukotriene synthesis and are therefore useful for the treatment of pul- monary, inflammatory, allergic and cardiovascular diseases. The compounds are also cytoprotective and therefore useful in the treatment of peptic ulcers.

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