2-amino-9[(2-hydroxymethyl)cyclopropylidenemethyl]purines as...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 473/38 (2006.01) A61K 31/52 (2006.01) A61P 31/12 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2479037

Compounds which are active against viruses have the Formulas (1) and (2), wherein B is 2-aminopurine-9-yl, which may be unsubstituted or substituted in the 6 position with NHR1, OR2, or SR3; Rl is selected from the group consisting of alkyl, alkenyl, alkynyl, and C4-18 cycloalkyl, any of which may be optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl; R2 is selected from the group consisting of C2-18 alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl, and aryl; and R3 is selected from the group consisting of alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl.

L'invention concerne des composés qui présentent une activité dirigée contre des virus. Ils sont représentés par les formules (1) et (2), dans lesquelles B représente 2-aminopurine-9-yle, qui peut non substitué ou substitué en position 6 par NHR¿1?, OR¿2?, ou SR¿3? ; R¿1? est sélectionné parmi alkyle, alcényle, alcynyle et cycloalkyle C¿4-18?, un ou plusieurs éléments du groupe formé par hydroxy, halo, amino, acyle, cycloalkyle, hétérocyclyle et aryle pouvant être substitués à ces derniers ; R¿2? est sélectionné parmi alkyle C¿2-18?, alcényle, alcynyle, et cycloalkyle, ces derniers pouvant être ramifiés ou linéaires, et un ou plusieurs éléments du groupe formé par hydroxy, halo, amino, acyle, cycloalkyle, hétérocyclyle et aryle pouvant être substitués à ces derniers; et R¿3? est sélectionné parmi alkyle, alcényle, alcynyle et cycloalkyle, ces derniers pouvant être ramifiés ou linéaires, et un ou plusieurs éléments du groupe formé par hydroxy, halo, amino, acyle, cycloalkyle, hétérocyclyle et aryle pouvant être substitués à ces derniers.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

2-amino-9[(2-hydroxymethyl)cyclopropylidenemethyl]purines as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-amino-9[(2-hydroxymethyl)cyclopropylidenemethyl]purines as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-amino-9[(2-hydroxymethyl)cyclopropylidenemethyl]purines as... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1631037

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.