C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
167/264, 260/553
C07K 5/06 (2006.01) A61K 31/16 (2006.01) C07C 237/06 (2006.01) C07C 237/20 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1315477
Abstract Compounds of general formula I, Image I wherein Ar1 and Ar2, which may be the same or different, represent phenyl optionally mono-substituted by fluorine, and R, R1, R2, R3 and R4 have the meanings given in the description, and pharmaceutically acceptable acid addition salts thereof, are useful as sedatives and in the treatment of epilepsy. The compounds are conveniently prepared by amide- forming reactions, and may be administered in the form of compositions comprising a pharmaceutically acceptable adjuvant, diluent or carrier.
588803
Fisons Corporation
Griffith Ronald C.
Pennwalt Corporation
Ridout & Maybee Llp
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