2-amino benzimidazole derivatives and their use as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 235/30 (2006.01) A61K 31/4184 (2006.01)

Patent

CA 2575882

This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

La présente invention concerne de nouveaux dérivés 2-amino benzimidazole qui conviennent comme modulateurs des canaux de potassium activés par calcium à faible conductance (canaux SK). Dans d'autres aspects, cette invention concerne l'utilisation de ces composés dans une technique de thérapie et des compositions pharmaceutiques comprenant les composés de l'invention.

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