2-amino-benzoic acid derivatives and processes for their...

Details 2-amino-benzoic acid derivatives and processes for their... 2-amino-benzoic acid derivatives and processes for their...

C - Chemistry, Metallurgy

07

D

260/277.1, 260/2

C07D 215/44 (2006.01) C07D 295/088 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1193598

ABSTRACT OF THE DISCLOSURE The present invention relates to new 2-aminoben- zoic acid derivatives having the general formula (I) Image ( I ) wherein R is either chlorine or trifluoromethyl; R' represents a radical having the general formula: -CH12-CH2- Image , wherein n is 0 or 1 and m is 4, 5 or 6; 2-tetrahydropyranylmethyl; benzyloxymethyl; benzoyl- oxymethyl or 1(3H)-isobenzofuranone-3-yl; and their pharmaceutically acceptable non-toxic addition salts; as well as processes for preparing these compounds. The compounds according to the invention exhibit a remarkable analgesic and anti-inflammatory activity.

427487

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