2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulfides and...

Details 2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulfides and... 2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulfides and...

C - Chemistry, Metallurgy

07

C

260/535.5, 260/5

C07C 155/10 (1980.01)

Patent

CA 1113492

ABSTRACT OF THE DISCLOSURE New 2-amino-cyclopent-1-ene-thiocarboxylic acid-disulfides of the general formula (I), Image (I) wherein R is a C1-6 alkyl group having optionally a C1-4 alkoxy, hydroxy, carboxy and/or amino substituent, a C2-4 alkenyl group, a C3-8 cycloalkyl group or benzyl group, are prepared by oxidizing the respective 2-amino- cyclopent-1-ene-dithiocarboxylic acids of the general formula (II), Image (II) wherein R is as defined above. The new compounds of the general formula (I) and their salts exert dopamine-.beta.-hydroxylase inhibiting effects and can be applied in the therapy.

294697

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