2-amino pyrimidine compounds as potent hsp-90 inhibitors

Details 2-amino pyrimidine compounds as potent hsp-90 inhibitors 2-amino pyrimidine compounds as potent hsp-90 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2732922

The present invention is directed to compounds of Formula (I), or pharmaceutically acceptable salts thereof, their synthesis, and their use as HSP-90 inhibitors in the treatment of proliferative diseases, e.g. cancer.

La présente invention concerne les composés de formule (I), ou des sels pharmaceutiquement acceptables de ceux-ci, leur synthèse et leur utilisation comme inhibiteurs de l'HSP-90 dans le traitement de maladies prolifératives, par exemple le cancer.

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