2-amino-quinaz0lin-5-ones

Details 2-amino-quinaz0lin-5-ones 2-amino-quinaz0lin-5-ones

C - Chemistry, Metallurgy

07

D

C07D 239/84 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 403/04 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 413/10 (2006.01) C07D 417/10 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2604942

2-Amino-quinazolin-5-one compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-quinazolin- 5-one compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cell proliferative diseases.

L'invention concerne des composés de 2-amino-quinazolin-5-one, des stéréoisomères, des tautomères, des sels acceptables pharmaceutiquement et des promédicaments associés, des compositions qui contiennent un excipient acceptable pharmaceutiquement et au moins un des composés de 2-amino-quinazolin-5-one, seul ou mélangé à un agent thérapeutique supplémentaire. Cette invention a aussi pour objet des méthodes d'utilisation des composés de 2-amino-quinazolin-5-one, seuls ou mélangés à au moins un agent thérapeutique supplémentaire, dans la prophylaxie ou le traitement de maladies à prolifération cellulaire.

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