2-aminobenzazapine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 223/16 (2006.01) A61K 31/55 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 487/04 (2006.01) C07D 491/056 (2006.01) C07D 495/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2213108

A compound of the formula: (see formula I) wherein preferably a is 1, V is CH or COCH3, X is CH or COCH3, Y is CH, COH, COCH3 or (see formula II), Z is CH or COCH3, R1 is H, -OCH2CH3 or -N(C3H7)2 and R2, R3 and R4 are each independently H, is useful in (a) the treatment of myelosuppression including suppression associated with cancer chemotherapy as well as activation of the immune system for the treatment of cancer or (b) prevention and treatment of viral, fungal, bacterial and parasitic infectious diseases.

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