2-aminobenzoxazole carboxamides as 5ht3 modulators

Details 2-aminobenzoxazole carboxamides as 5ht3 modulators 2-aminobenzoxazole carboxamides as 5ht3 modulators

C - Chemistry, Metallurgy

07

D

C07D 451/14 (2006.01) A61K 31/439 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 453/02 (2006.01)

Patent

CA 2660349

Compounds of Formulae (I), (II) and (III): are disclosed as 5-HT3 inhibitors. The compounds are useful in treating CINV, IBS-D and other diseases and conditions.

L'invention concerne des composés de formule I, II et III utilisés comme inhibiteurs de 5-HT3. Les composés sont utiles pour traiter des nausées et vomissements provoqués par la chimiothérapie (NVPC), un syndrôme du côlon irritable à prédominance de diarrhée (IBS-D) et d'autres maladies et conditions.

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