(2-aminoethyl) oxime derivatives for the treatment of...

A - Human Necessities – 61 – K

Patent

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A61K 31/215 (2006.01) A61K 31/192 (2006.01) A61K 31/221 (2006.01) A61K 31/277 (2006.01) A61K 31/4015 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) C07C 251/58 (2006.01)

Patent

CA 2405025

The subject invention provides compounds which are easily metabolized by the metabolic drug detoxification systems. Particularly, fluvoxamine analogs which have been designed to include esters within the structure of the compounds are taught. Also povided are methods of treating depression and affective disorders, such as obsessive compulsive disorder. Pharmaceutical compositions of the fluvoxamine analogs are also taught.

concerne des composés qui sont facilement métabolisées par les systèmes métaboliques de détoxication des médicaments. D'une manière spécifique, l'invention concerne des analogues de la fluvoxamine conçu pour comporter des esters dans la structure des composés. L'invention concerne également des méthodes permettant de traiter la dépression et des troubles affectifs, tels que des troubles obsessionnels compulsifs. L'invention concerne en outre des compositions pharmaceutiques de ces analogues de la fluvoxamine.

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